Molecular Structure of Biological Materials (BE.442)

Lecture Notes

LEC #	TOPICS
1	Important Role of Water Molecule, Hydration of Amino Acids, Protein and other Biological Materials (PDF)
2	Amino Acids: Their Chemical and Physical Properties (PDF)
3	Primary and Secondary Structures of Proteins Dihedral Angles, Peptide Bonds, Planar Structure, Relationship and Propensity of Amino Acid Sequence, Secondary Structure Ramachandran Plot
4	Alpha-helices, 310 Helix, pi Helix, Beta-helices, etc. Variation of Helices and their Helical Bundles, Two Strand Coiled-coils, Three or Four Strand Coiled-coils, Supercoils Various Helical Rich Protein Structure Models Alpha-helices in Biological Materials
5	Helical Coiled-coils Two-, Three-, Four- Stranded Helical Bundles Applying Coiled-coils to Nanomaterials, Molecular Springs, Switches, etc.
6	Beta Sheets: Antiparallel, Parallel, and Twist; Beta Sheet Rich Proteins; Beta Sheets in Biological Materials (PDF)
7	Practical Aspects of Single Crystal X-ray Crystallography, Part 1: X-ray Single Crystal Diffraction, Fiber Diffraction, and Preparation of Samples (PDF)
8	NMR (Guest Lecturer: Peter Carr, MIT Media Lab) (PDF)
9	Practical Aspects of Single Crystal X-ray Crystallography, Part 2 (PDF)
10	Analytical Approaches and Instrumentation (Guest Lecturer: Sotirus Koutsopoulos, Ph.D) (PDF)
11	Silk (PDF)
12	Biomineralization: Sea Creatures (PDF)
13	Biomineralization: Bones and Teeth (PDF)
14	Bioadhesives (PDF)
15	Lipids as Building Materials (PDF)
16	Polysaccharides and Oligosaccharides (PDF)
17	Francis Crick Film
18	Molecular Structure and Self-assembly of DNA and RNA (PDF)
19	Macromolecular Interactions and Protein and Adsorption (Guest Lecturer: Larry Unsworth, Ph.D, National Institute for Nanotechnology) (PDF) Crystallography (Guest lecturer: Liselotte Kaiser, MIT Center for Biomedical Engineering)
20	DNA Molecular Machines (PDF)
21	Fluorescent Proteins (PDF)
22	Self-assembling Peptide Systems (Dr. Zhang’s Research) (PDF)
23	Self-assembling Peptide Systems (Dr. Zhang’s Research) (cont.) (PDF) Applying Biomimicry to Nanotechnology (Guest Lecture by Andreas Mershin)
24	Research in Biomaterials (PDF)
25-26	Student Research Activity Presentations