This page presents the lecture notes for each class session, plus supporting multimedia for some sessions.
| LEC # | TOPICS | SUPPORTING MULTIMEDIA |
|---|---|---|
| 1 | Introduction to nanomechanics (PDF) | Feynman, Richard. Tiny Machines. Audio CD, Sound Photosynthesis, 1984. |
| 2 | High resolution force spectroscopy (HRFS): The force transducer (PDF) | |
| 3 | Additional nanomechanics instrumentation components (PDF) | |
| 4 | Force versus distance curves (PDF) | |
| 5 | Atomic force microscope (AFM) imaging (PDF) |
Video: “Understanding AFM” Force curve animation, from NC State University (MOV) |
| 6 | AFM imaging II: Artifacts and applications (PDF) | |
| 7 | Single cell mechanics (PDF) | |
| 8 | Qualitative Introduction to intra- and intermolecular forces (PDF) | Protein Folding demo [You will need the MDL Chime plugin for your browser, which is a free download.] |
| 9 | Quantitative description of intra- and intermolecular forces (PDF) | |
| 10 | Molecule-surface interactions (PDF) | |
| 11 | Colloids and interparticle potentials (PDF) | |
| 12 | Van der Waals forces at work: Gecko feet adhesion (PDF) | |
| 13 | Midterm exam solutions review (PDF) | |
| 14 | The electrical double layer (EDL) - part 1 (PDF) | |
| 15 | The electrical double layer (EDL) - part 2 (PDF) | |
| 16 | Nanomechanics of cartilage (PDF - 2.0 MB) | |
| 17 | Protein-surface interactions (PDF - 1.3 MB) |
John Marko, Cornell University, 1994. Simulation of Polymer Brush Interacting with Nanosized Object (AVI) (Courtesy of Jan Hoh. Used with permission.) |
| 18 | Nanomechanics and biocompatibility: Protein-biomaterial interactions, part 2 (PDF) | Same as prior session. |
| 19 | Elasticity of single polymer chains: Theoretical formulations (PDF) | |
| 20 | Theoretical aspects of single molecule force spectroscopy: Extensibility and the worm-like chain (WLC) (PDF) | |
| 21 | Single chain elasticity of biomacromolecules: The giant protein titin and DNA (PDF) |
From the Theoretical and Computational Physics Group, UIUC: Movie of SMFS Fibronectin stretching (MPEG - 1.7 MB) |
| 22 | Theoretical aspects of nanoindentation (PDF) | |
| 23 | Nanoindentation 2: Oliver-Pharr method and one literature example: Nacre (PDF - 1.0 MB) | |
| 24 | Intermolecular interactions in motility of a biological spring (guest lecture by Danielle France, course TA) |
