EC.710 | Spring 2010 | Undergraduate

D-Lab: Medical Technologies for the Developing World

Labs and Readings

1 Drug delivery

Mizrahi, Boaz, and Abraham J. Domb. “Mucoadhesive Tablet Releasing Iodine for Treating Oral Infections.” Journal of Pharmaceutical Sciences 96, no. 11 (2007): 3144-50.

Shemer, Avner, et al. “Efficacy of a Mucoadhesive Patch Compared with an Oral Solution for Treatment of Aphthous Stomatitis.” Drugs in R&D 9, no. 1 (2008): 29-35.

2 Diagnostics

Chin, Curtis D., Vincent Linder, and Samuel K. Sia. “Lab-on-a-Chip Devices for Global Health: Past Studies and Future Opportunities.” Lab Chip 7, no. 1 (2007): 41-57.

Yuen, Po Ki, and Vasiliy N. Goral. “Low-Cost Rapid Prototyping of Flexible Microfluidic Devices Using a Desktop Digital Craft Cutter.” Lab Chip 10, no. 3 (2010): 384-7.

Kaigala, Govind V., et al. “Rapid Prototyping of Microfluidic Devices with a Wax Printer.” Lab Chip 7, no. 3 (2007): 384-7.

Martinez, Andres W., Scott T. Phillips, and George M. Whitesides. “Three-dimensional Microfluidic Services Fabricated in Layered Paper and Tape.” Proceedings of the National Academy of Sciences 105, no. 50 (2008): 19606-11.

Paper diagnostics Combur-10 test: Combur-Test® Product Line. Roche Diagnotics. Accessed December 20, 2010.

Grifantini, Kristina. “TR10: Paper Diagnostics.” Technology Review, March/April 2009.

Urdea, Mickey, et al. “Requirements for High Impact Diagnostics in the Developing World.” Nature (published online November 22, 2006): 73-9.

3 Instrumentation  
4 Vital signs monitoring  
5 Microfluidics

Schilling, Eric, and Paul Yager. “Basic Microfluidic Concepts.” September 7, 2001. Accessed August 25, 2009.

Goho, Alexandra. “Diagnosing the Developing World: Turning High-tech Innovations into Low-cost Medical Tests.” Science News, February 14, 2004.

Sia, Samuel K., and Larry J. Kricka. “Microfluidics and Point-of-Care Testing.” Lab Chip 8, no. 12 (2008): 1982-3.

Sia, Samuel K., and George M. Whitesides. “Microfluidic Devices Fabricated in Poly(dimethylsiloxane) for Biological Studies.” Electrophoresis 24, no. 21 (2003): 3563-76.

U.S. CDC and WHO. “Overview of HIV Testing Technologies.” Module 3 in HIV Rapid Testing Training Package, Participant Manual, 2005. (PDF)

6 Visit to Shriners Hospital for Children, Boston, MA  
7-13 Project team work  

Course Info

As Taught In
Spring 2010
Learning Resource Types
Design Assignments with Examples