HST.582J | Spring 2007 | Graduate
Biomedical Signal and Image Processing

Lecture Notes

Some of the lecture notes are chapters derived from 1999-2001 course notes written by Dr. Bertrand Delgutte. Chapter 9 was also originally co-authored by Paul Albrecht. These chapters are presented courtesy of the authors and used with permission.

Key to instructors: 
JG = Dr. Julie Greenberg 
JF = Dr. John Fisher 
SW = Dr. William Wells 
GC = Dr. Gari Clifford

1 Data acquisition JG

Introduction to Biomedical Signal and Image Processing (PDF)

Chapter 1: data acquisition (PDF)

2 Digital filtering JG Chapter 2: digital filters (PDF)
3 ECG Guest: Andrew Reisner, MD

Slides: Introduction to Clinical Electrocardiography (PDF - 1.3 MB) (Courtesy of Andrew Reisner, MD. Used with permission.)


Reisner, A. T., G. Clifford, and R. Mark. “The Physiological Basis of the Electrocardiogram.” Chapter 1 in Advanced Methods and Tools for ECG Data Analysis. Edited by Clifford, G., F. Azuaje, and P. McSharry. Norwood, MA: Artech House, 2006. ISBN: 9781580539661. (PDF)

4 DTFT JG Chapter 3: Fourier representation of signals and systems (PDF)
5 DFT JG Chapter 4: the discrete Fourier transform (PDF)
6 Sampling revisited JG

Chapter 5: sampling in time and frequency (PDF)

Background Reading

Chapter 6: Z-transforms (PDF) (not covered in class, but distributed for completeness)

7 Speech signals JG

Quatieri, T. F. “Production and Classification of Speech Sounds.” Chapter 3 in Discrete-Time Speech Signal Processing: Principles and Practice. Upper Saddle River, NJ: Prentice-Hall, 2001. ISBN: 9780132429429.

Chapter 7: the short-time Fourier transform (PDF)

8 Speech coding JG

Chapter 7: the short-time Fourier transform (cont. from prior session)

Chapter 8: linear prediction (PDF)

9 Image processing I JG Chapter 9: image processing (PDF)
10 PDFs JF

Slides for Lec #10 and #11: decision systems (PDF)

Probability primer (PDF), Venn diagrams (PDF)

11 Classification JF Slides continued from prior session
12 Image processing II SW Image processing 2 (PDF)
13 Estimating PDFs JF Decision systems 2 - density estimation (PDF)
14 Segmentation SW Introduction to medical image segmentation (PDF - 1.0 MB)
15 Image registration I Guest: Lilla Zöllei Slides (PDF - 1.3 MB) (Courtesy of Lilla Zöllei. Used with permission.)
16 Image registration II Guest: Lilla Zöllei Slides (PDF - 2.5 MB) (Courtesy of Lilla Zöllei. Used with permission.)
17 Imaging modalities SW Medical image modalities (PDF - 1.6 MB)
18 Random signals I JF

Slides for Lec #18 and #19: random signal processing (PDF - 1.5 MB)


Chapter 11: random signals – basic properties (PDF)

19 Random signals II JF

Slides continued from prior session


Chapter 12: random signals and linear systems (PDF)

20 Blind source separation GC

Lecture slides (PDF - 1.8 MB)


Chapter 15: blind source separation (PDF - 1.3 MB)

21 MRI Guest: R. V. Mulkern, PhD Department of Radiology, Children’s Hospital Boston  
22 Surgical applications    
23 Random signals III    
24 End of term wrap-up JG