Instructor key:
[MBY] = Prof. Michael B. Yaffe
[MVH] = Prof. Matthew Vander Heiden
| lec # | topic | instructor | key dates |
|---|---|---|---|
| Part I: Biomolecules, Methods, and Mechanisms | |||
| 1 | Introduction; Classes of Biomolecules; pH, Buffers and Titration Curves | MBY | Problem Set 1 Assigned |
| 2 | Amino Acids and Proteins | MBY | |
| 3 | Protein Purification I | MBY |
Problem Set 1 Due Problem Set 2 Assigned |
| 4 | Protein Purification II, Protein Structure II | MBY | |
| 5 | Protein Structure II, Protein Folding | MBY | |
| 6 | Hemoglobin and Allostery | MBY |
Problem Set 2 Due Problem Set 3 Assigned |
| 7 | Hemoglobin and the Bohr Effect | MBY | |
| 8 | Enzyme Chemistry | MBY | |
| 9 | Enzymes as Catalysts | MBY |
Problem Set 3 Due Problem Set 4 Assigned |
| 10 | Enzyme Mechanisms | MBY | |
| 11 | Enzyme Kinetics | MBY | Problem Set 4 Due |
| Exam 1: Focus on Lectures 1 – 10 | Problem Set 5 Assigned | ||
| 12 | Carbohydrates/Introduction to Membranes | MVH | |
| 13 | Channels, Transporters & Pumps, Protein Modules | MBY | |
| 14 | Hormones and Signal Transduction I | MBY |
Problem Set 5 Due Problem Set 6 Assigned |
| 15 | Receptors, Small G-proteins and Signal Transduction II | MBY | |
| 16 | Nucleic Acids | MBY | |
| 17 | tRNAs and Protein Translation | MBY | Problem Set 7 Assigned> |
| 18 | Translation and the Ribosome | MBY | Problem Set 6 Due |
| Exam 2: Focus on Lectures 11 – 16 | |||
| Part II: Metabolism | |||
| 19 | Introduction Metabolism Polysaccharides/Bioenergetics/Intro Pathways | MVH | |
| 20 | Bioenergetics/Intro Pathways/Glycolysis I | MVH | |
| 21 | Glycolysis II/Gluconeogenesis | MVH |
Problem Set 7 Due Problem Set 8 Assigned |
| 22 | Carbohydrate Storage/TCA Cycle I | MVH | |
| 23 | TCA Cycle II | MVH | |
| 24 | Lipids and Fatty Acid Oxidation/Oxidative Phosphorylation I | MVH |
Problem Set 8 Due Problem Set 9 Assigned |
| Exam 3: Focus on Lectures 17 – 23 | |||
| 25 | Oxidative Phosphorylation II | MVH | Problem Set 10 Assigned |
| 26 | Photosynthesis I | MVH |
Problem Set 9 Due |
| 27 | Photosynthesis II/CO2 Assimilation | MVH | |
| 28 | Pentose Phosphate Pathway | MVH |
Problem Set 10 Due Problem Set 11 Assigned |
| 29 | Lipid Synthesis | MVH | |
| 30 | Nitrogen/Amino Acid Metabolism I | MVH | |
| 31 | Amino Acid Metabolism II | MVH | Problem Set 11 Due |
| 32 | Nucleotide Metabolism | MVH | |
| Exam 4: Focus on lectures 24 – 32 | |||
