5.07SC | Fall 2013 | Undergraduate

Biological Chemistry I

Module I: Basic Biochemistry

Session 3: Enzymes and Catalysis

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Lecture Topics

  • Definition of a Catalyst
  • Conceptualization of Catalysis using Transition State Theory
  • How has Nature Evolved Enzymes to Lower the Activation Barrier?
  • The Second Important Property of Enzymes is their Specificity


  • Chapter 11: Enzymatic Catalysis
    • General Properties of Enzyme
    • Activation Energy and the Reaction Coordinate
    • Catalytic Mechanisms
    • Serine Proteases

Lecture Video: Enzymes and Catalysis

In this classroom lecture, Professor Stubbe focuses on enzymes as catalysts. She describes the theory and mechanics of catalysis and explains why enzymes are so important.

Lecture Notes

Problem Set & Solutions

Problem Solving Video: Problem Set 2, Problem 1: Primary Structure

This problem is about elucidating the primary structure of a protein. Dr. Fedeles uses traditional chemical methods to analyze the data and produce a big picture result. This is the very same process by which discoveries are made.

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Course Info

As Taught In
Fall 2013
Learning Resource Types
Lecture Videos
Other Video
Problem Sets with Solutions
Lecture Notes
Instructor Insights