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Looking for something specific in this course? The Resource Index compiles links to most course resources in a single page.
Module III: Using Energy to Make Macromolecules
Lecture Topics
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Readings
- Chapter 20: Lipid Metabolism
- Lipid Digestion, Absorption, and Transport
- Fatty Acid Oxidation
- Ketone Bodies
- Fatty Acid Biosynthesis
- Regulation of Fatty Acid Metabolism
Lecture Video: Fatty Acid and Lipid Biosynthesis
This video introduces anabolism, the phase of metabolism in which complex molecules are formed from simpler ones. Professor Essigmann describes in detail stages of fatty acid biosynthesis and lipid biosynthesis.
Lecture Topics
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Readings
- Chapter 16: Glycogen Metabolism and Gluconeogenesis
- Glycogen Synthesis
- Control of Glycogen Metabolism
- Gluconeogenesis
Lecture Video: Carbohydrate Biosynthesis I: Glycogen Synthesis
This first of two videos on carbohydrate biosynthesis focuses on glycogen synthesis, also called glycogenesis. Professor Essigmann describes the pathway by which we form glycogen – the form of glucose that is readily available for energy production.
Lecture Topics
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Readings
- Chapter 16: Glycogen Metabolism and Gluconeogenesis
- Gluconeogenesis
Lecture Video: Carbohydrate Biosynthesis II: Gluconeogenesis
This video focuses on gluconeogenesis (GNG) – the synthesis of glucose from noncarbohydrate precursors. Professor Essigmann explains why this process is particularly important to organs of the body that require glucose as their primary metabolic fuel.
Problem Set & Solutions
Problem Solving Video: Problem Set 10, Problem 3: Gluconeogenesis
Gluconeogenesis is a spontaneous process that involves the synthesis of glucose from non-sugar precursors. In this problem, Dr. Fedeles examines the mechanisms of gluconeogenesis, which require several steps of glycolysis to run in the reverse direction.
Lecture Topics
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Readings
- Chapter 15: Glucose Catabolism
- The Pentose Phosphate Pathway
Lecture Video: Pentose Phosphate Pathway
In this video, Professor Essigmann reviews the Pentose Phosphate Pathway (PPP). He describes in detail the two distinct modes in the pathway: the oxidative mode and the non-oxidative mode.
Lecture Topics
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Readings
- Chapter 22: Mammalian Fuel Metabolism: Integration and Regulation
- Organ Specialization
- Hormonal Control of Fuel Metabolism
- Disturbances in Fuel Metabolism
Lecture Video: Regulation of Metabolism
In this final video, Professor Essigmann considers cell to organ and organ to organism metabolism. He reviews the key organ systems and hormones, and describes the general paradigms of pathway control: Covalent, Allosteric, and Acceptor Control.
Course Info
Departments
As Taught In
Fall
2013
Level
Topics
Learning Resource Types
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Lecture Videos
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Problem Sets with Solutions
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