Biological Chemistry I

Session 19: Carbohydrate Biosynthesis II: Gluconeogenesis

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Lecture Topics

Gluconeogenic (GNG) Precursors GNG Pathway Overview Mechanisms of GNG Enzymes GNG Pathway Details

Readings

• Chapter 16: Glycogen Metabolism and Gluconeogenesis
  • Gluconeogenesis

Lecture Video: Carbohydrate Biosynthesis II: Gluconeogenesis

This video focuses on gluconeogenesis (GNG) – the synthesis of glucose from noncarbohydrate precursors. Professor Essigmann explains why this process is particularly important to organs of the body that require glucose as their primary metabolic fuel.

• Storyboards 31–32 (PDF)

Problem Set & Solutions

• Problem Set 10 (PDF)
• Solutions to Problem Set 10 (PDF)

Problem Solving Video: Problem Set 10, Problem 3: Gluconeogenesis

Gluconeogenesis is a spontaneous process that involves the synthesis of glucose from non-sugar precursors. In this problem, Dr. Fedeles examines the mechanisms of gluconeogenesis, which require several steps of glycolysis to run in the reverse direction.

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