16.423J | Spring 2006 | Graduate

Aerospace Biomedical and Life Support Engineering

Readings

SES # TOPICS READINGS
1 Introduction “Human Anatomy Manual: The Skeleton.” Gatesville, TX: Medical Plastics Laboratory, Inc., 1997.

Beckers, Frank, Bart Verheyden, Andre E. Aubert. “Space Physiology.” Wiley Encyclopedia of Biomedical Engineering. Hoboken, NJ: John Wiley and Sons, Inc., 2006. ISBN: 9780471740377 .

National Academies Committee on Science, Engineering, and Public Policy. “Rising above the Gathering Storm: Energizing and Employing America for a Brighter Economic Future.” Washington, DC: The National Academies Press, 2006.

Markoff, John. “Behind Bush’s New Stress on Science, Lobbying by Republican Executives.” The New York Times, February 2nd, 2006.

2 Humans in Space “Space Science and Exploration: Research and Development Funding in the President’s 2007 Budget.” Office of Science and Technology Policy, Executive Office of the President, Washington, DC, 2006.

“Math and Science Eduction: American Competitiveness Initiative Education Funding in the President’s 2007 Budget.” Office of Science and Technology Policy, Executive Office of the President, Washington, DC, 2006. (PDF)

2007 US Federal R&D Budget Facts. (PDF)

“NASA’s Exploration Systems Architecture Study.” Executive Summary. ( PDF - 4.9 MB)

3 Exploration in Extreme Environments Stuster, J. “Bold Endeavors: Behavioral Lessons from Polar and Space Exploration.” Gravitational and Space Biology Bulletin 13, no. 2 (June 2000).

Stuster, J., C. Bachelard, and P. Suedfeld. “The Relative Importance of Behavioral Issues during Long-duration ICE Missions.” Aviat. Space Env. Med. (September 2000): A17-A25.

Brubakk, A. “Man in Extreme Environments.” Aviat. Space Env. Med. (September 2000): A126-A130.

4 Bone Changes in Space Schaffner, Grant. “Bone Changes in Weightlessness.” (PDF - 2.0 MB)

Beck, T. J., C. B. Ruff, et al. “Predicting Femoral Neck Strength from Bone Mineral Data: A Structural Approach.” Investigative Radiology 25, no. 1 (1990): 6-18.

Beck, T. J., F. A. Mourtada, et al. “Experimental Testing of a DEXA-Derived Curved Beam Model of the Proximal Femur.” Journal of Orthopaedic Research 16, no. 3 (1998): 394-398.

Gibson, Lorna. “Biomechanics of Cellular Solids.” Journal of Biomechanics 38, no. 3 (2005): 377-399.

Frost, H.M. “Why Do Marathon Runners Have Less Bone than Weight Lifters? A Vital-Biomechanical View and Explanation.” Bone 20, no. 3 (1997): 183-189.

5 Muscle Mechanisms I Shenkman, Boris S., and Inessa B. Kozlovskaya. “Results of Studies of the Effects of Space Flight Factors of Human Physiological Systems and Psychological Status, and Suggestions of Future Collaborative Activities between the NSBRI and the IBMP.” Section 3: Muscles. State Research Center of Russian Federation Institute for Biomedical Problems Report, Moscow, 2000.
6 Muscle Mechanisms II  
7 Motor Control Optimization  
8 Quiz 1  
9 Musculoskeletal Dynamics and Control

Bizzi, E., W. Chapple, and N. Hogan. “Mechanical Properties of Muscles: Implications for Motor Control.” Trends in Neurosciences 5, no. 11 (1982): 395-398.

Flash, T., and N. Hogan. “The Coordination of Arm Movements: An Experimentally Confirmed Mathematical Model.” Journal of Neuroscience 5, no. 7 (1985): 1688-1703.

Flash, T. “The Control of Hand Equilibrium Trajectories in Multi-joint Arm Movements.” Biological Cybernetics 57 (1987): 257-274.

Gribble, P. L., D.J. Ostry, V. Sanguineti, and R. Laboissiere. “Are Complex Control Signals Required for Human Arm Movement?” Journal of Neurophysiology 79 (1998): 1409-1424.

Gomi, Hiroaki, and Mitsuo Kawato. “Equilibrium-Point Control Hypothesis Examined by Measured Arm Stiffness during Multijoint Movement.” Science 272, no. 5258 (1996): 117-120.

10 Cardiovascular System Fritsch-Yelle, Janice M., Urs A. Leuenberger, Dominick S. D’Aunno, Alfred C. Rossum, Troy E. Brown, Margie L. Wood, Mark E. Josephson, and Ary L. Goldberger. “An Episode of Ventricular Tachycardia during Long-Duration Spaceflight.” The American Journal of Cardiology 81 (1998): 1391-1392.

Kirsch, K.A., L. Rocke, O.H. Gauer, R. Krause, C. Leach, H.J. Wicke, and R. Landry. “Venous Pressure in Man during Weightlessness.” Science 225, no. 4658 (1984): 218-219.

Aubert, A.E., F. Beckers, and B. Verheyden. “Cardiovascular Function and Basics of Physiology in Microgravity.” Acta Cardiol 60, no. 2 (2005): 129-151.

11 Cardiovascular Control  
12 Cardiovascular Simulation Heldt, Shim, and Mark Kamm. “Computational Modeling of Cardiovascular Response to Orthostatic Stress.” Journal of Applied Physics 92 (2002): 1239-1254.

Convertino, V.A., and W.H. Cooke. “Evaluation of Cardiovascular Risks of Spaceflight Does Not Support the Bioastronautics Critical Path Roadmap.” Aviat. Space Environ. Med. 76, no. 9 (2005): 869-76.

13 Countermeasures and Artificial Gravity Diamandis, Peter H. “Countermeasures and Artificial Gravity.” Chapter 12 in Fundamentals of Space Life Sciences. Edited by Susanne Churchill. Malabar, FL: Krieger Publishing Co., 1997. ISBN: 9780894640513 .

Stone, Ralph W., Jr. “An Overview of Artificial Gravity.” Fifth Symposium on the Role of the Vestibular Organs in Space Exploration, Pensacola, Florida, August 19-21, 1970, NASA SP-314, 1973, pp. 23-33.

14 Extravehicular Activity (EVA)

  •  Newman, Dava, and Michael Barratt. “Life Support and Performance Issues for Extravehicular Activity (EVA).” Chapter 22 in Fundamentals of Life Sciences. Edited by Susanne Churchill. Malabar, FL: Krieger Publishing Co., 1997. ISBN: 9780894640513 .
15 EVA II: Research  
16 Teaching and Outreach I NASA Education Home

NASA Lessons for K-12 Students

17 Teaching and Outreach II National Academy of Engineering

National Academy Report: Raising the Public Awareness of Engineering

Educating the Engineer of 2020: Adapting Engineering Education to the New Century (2005)

Learning Resource Types
Problem Sets with Solutions
Exams with Solutions
Written Assignments