Biochemistry

Proteins, Levels of Structure, Non-Covalent Forces

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Session Overview

Biochem_sess4.jpg

This session will introduce the general composition, structure, and function of proteins. The relationship between structure and function of a protein will be emphasized.

Learning Objectives

  • To understand the general composition of a protein.
  • To draw a generic amino acid and categorize each of the 20 amino acids appropriately based upon the nature of the side chain.
  • To understand primary, secondary, tertiary, and quaternary levels of protein structure and know what types of bonds and forces stabilize each level.
  • To understand the effect of an amino acid substitution on the general structure and function of a protein.

Session Activities

Lecture Video

Watch the lecture video excerpt

Check Yourself

Question 1

How many different functional groups are attached to the alpha carbon of an amino acid?

1 close
2 close
3 close
4 check
5 close
Check

Question 2

A polypeptide chain is polymerized in which direction?

3’ to 5’ close
5’ to 3’ close
Amino to carboxyl check
Carboxyl to amino close
Check

Question 3

Which of the following can be described as “a localized region of three dimensional structure that is stabilized by hydrogen bonds formed between the amine of one amino acid and the carboxyl of another amino acid”?

primary structure close
quaternary structure close
secondary structure check
tertiary structure close
Check

Session Activities

Lecture Video

Watch the lecture video excerpt

Check Yourself

Structures of the 20 amino acids (PDF)

Question 1

The amino acids leucine, valine, and phenylalanine would best be described as…

non-polar check
polar and negatively charged close
polar and positively charged close
polar and uncharged close
Check

Question 2

The side chain of serine can form a hydrogen bond with the side chain of which of the following amino acids? Choose all that apply. 1. isoleucine 2. alanine 3. threonine 4. asparigine 5. proline

a, b, c close
a, b, c, d, e close
c, d check
d, e close
Check

Session Activities

Practice Problems

Further Study

Study Guides

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Learning Resource Types

theaters Recitation Videos
assignment_turned_in Problem Sets with Solutions
grading Exams with Solutions
theaters Lecture Videos