SES # | TOPICS | KEY DATES |
---|---|---|

1 | Introduction; Master equation | |

2 | Elements of population genetics | |

3 | Evolving populations (forward Kolmogorov) | |

4 | Population genetics (fitness, selection, …) | |

5 | Fixation (backward Kolmogorov) | |

6 | Introduction to sequence alignment | Assignment 1 due |

7 | Algorithms for sequence alignment | |

8 | Significance of alignments (extreme value distributions) | |

9 | Ionic interactions | Assignment 2 due |

10 | Polymer theory 1, entropy elasticity, collapse | |

11 | Polymer theory 2, collapse, Random energy model | |

12 | Protein folding I: elements of structure and forces | Assignment 3 due |

13 | Protein folding II: evolved (designed) foldable proteins | |

14 | Protein folding III: kinetics | Assignment 4 due |

15 | Protein folding IV:: kinetics | |

16 | DNA (melting) | |

17 | RNA (secondary structure) | Assignment 5 due |

18 | Protein-DNA interactions I: specific and non-specific binding | |

19 | Protein-DNA interactions II: sequence-dependence & kinetics | Assignment 6 due |

20 | Microtubules | |

21 | Molecular motors & cell motility | Assignment 7 due |

22 | Introduction to networks | |

23 | Dynamics on networks 1 | |

24 | Dynamics on networks 2 | Assignment 8 due |

25 | Packing of DNA inside cells | |

26 | Cooperativity: hemoglobin and transcription factors | Final Project due |

## Calendar

## Course Info

##### Instructors

##### Departments

##### As Taught In

Spring
2011

##### Level

##### Topics

##### Learning Resource Types

*assignment*Problem Sets

*notes*Lecture Notes

*group_work*Projects

*Instructor Insights*