Statistical Physics in Biology

Fixation

1. The backward Kolmogorov equation:
   • Steady states with absorbing states
   • Derivation of the backward Kolmogorov equation
2. Fixation:
   • General solution of the backward Kolmogorov equation
   • Fixation probability with selection
   • Fixation probability of a new mutation
3. Mean first passage times:
   • Mean time to fixation
   • Mean time to loss
   • Mean survival time

(Detailed Lecture Notes (PDF))