Instructors MK: Prof. Mehran Kardar LM: Prof. Leonid Mirny SES # TOPICS INSTRUCTORS 1 Introduction; Master equation MK 2 Elements of population genetics LM 3 Evolving populations (forward Kolmogorov) MK 4 Population genetics (fitness, selection, …) LM 5 Fixation (backward Kolmogorov) MK 6 Introduction to sequence alignment LM 7 Algorithms for sequence alignment LM 8 Significance of aligments (extreme value distributions) MK 9 Ionic interactions MK 10 Polymer theory 1, entropy elasticity, collapse MK 11 Polymer theory 2, collapse, Random energy model MK 12 Protein folding 1: elements of structure and forces LM 13 Protein folding 2: evolved (designed) foldable proteins LM 14 Protein folding 3: kinetics LM 15 Protein folding 4: kinetics LM 16 DNA (melting) MK 17 RNA (secondary structure) MK 18 Protein-DNA interactions 1: specific and non-specific binding LM 19 Protein-DNA interactions 2: sequence-dependence & kinetics LM 20 Microtubules MK 21 Molecular motors & cell motility MK 22 Introduction to networks MK 23 Dynamics on networks 1 MK 24 Dynamics on networks 2 LM 25 Packing of DNA inside cells LM 26 Cooperativity: hemoglobin and transcription factors LM