8.592J | Spring 2011 | Graduate

Statistical Physics in Biology

Lecture Notes

Microtubules

  1. Filaments in the cycloskeleton; Major types:
  2. Microtubule structure:
    • Tubulin subunits
    • Protofilaments, nucleation and growth
    • Polarity
  3. Dynamic Instability [Mitchison, T., and M. Kirchner. “Microtubule Assembly Nucleated by Isolated Centrosomes.” Nature 312, (1984): 232.]
  4. Search strategy
  5. Ndlec, F.J., et al. “Self-organization of microtubules and motors.” Nature 389, (1997): 305-308.

(Detailed Lecture Notes (PDF))

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