Biological Chemistry I

Session 11: Prochirality and Aconitase

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Lecture Topics

A Radiolabeled Atom in a TCA Cycle Intermediate Sometimes Does Chemically Unexpected Things Studies of the TCA Cycle Enzymes Aconitase and Citrate Synthase Helped Resolve This Vexing Issue Examination of the details of the TCA Cycle to See How non-TCA Cycle Intermediates Flow in to Sustain H

Readings

• Chapter 17: Citric Acid Cycle
  • Enzymes of the Citric Acid Cycle
  • Regulation of the Citric Acid Cycle
  • Reactions Related to the Citric Acid Cycle

Lecture Video: PLP (Pyridoxal Phosphate) Reactions

Lecture Video:

• Narrated Storyboards 8-9: TCA Cycle [John Video] Watch only narration of Storyboard 9 [time -> ]
  • Storyboard 9 (PDF)

Problem Set & Solutions 

• Problem Set 7 (PDF)
• Solutions to Problem Set 7 (PDF)

Problem Solving Video: Problem Set 7, Problem 1: Tracing Labels through Pathways

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