5.07SC | Fall 2013 | Undergraduate

Biological Chemistry I

Module II: Production of Energy in the Cell

Session 16: Ketogenesis, Diabetes and Starvation

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Lecture Topics

  • Ketone Body Facts
  • Ketone Body Formation
  • Ketone Body Utilization
  • Diabetes Scenario (Starvation)


  • Chapter 20: Lipid Metabolism
    • Ketone Bodies

Lecture Video: Ketogenesis, Diabetes and Starvation

In this video, Professor Essigmann explores ketone bodies – what they are, how they are made, and how they are used in the body. He describes in detail the role ketone bodies play in diabetes and starvation scenarios.

Bonus Video 1: The Science Behind Type II Diabetes

Professor Essigmann, who has Type II Diabetes, talks about his experience with the disease and the science behind it.

Bonus Video 2: Blood Sugar Fluctuations and Gluconeogenesis

The blood sugar of a diabetic fluctuates throughout the day. Professor Essigmann explores the concept of gluconeogenesis, the metabolic pathway that leads to the synthesis of glucose from non-carbohydrate precursors.

Bonus Video 3: When Your Breath Smells Like Nail Polish Remover

What does it mean when your breath smells like nail polish remover? In this video, Prof. Essigmann describes the role of acetone in Type II Diabetes.

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Course Info

As Taught In
Fall 2013
Learning Resource Types
Lecture Videos
Other Video
Problem Sets with Solutions
Lecture Notes
Instructor Insights